This study aims to use geographic information systems to analyze the spatial distribution of ATMs in Abha city. This is based on the most important applied aspects of geographic information systems, namely spatial analysis, to reveal the characteristics of the spatial distribution of ATMs and their distribution pattern, and to evaluate the efficiency of their distribution according to spatial variables. The study came out with a number of results and recommendations, the most important of which is increasing the number of (...) ATMs in high-density neighborhoods that are deprived of service, which reduces the pressure on them, in a way that ensures their sustainability, and in a manner that is proportional to both the area and the number of residents in the city's neighborhoods. (shrink)

Service geography is one of the branches of applied geography that has emerged as an applied intellectual interest to engage with the immediate direct needs of both urban and rural communities. The importance of studying services is due to their connection to economic planning, so geographical interest in them increases, as applied geography is based on a specific approach and philosophy of relevance or social benefit that focuses on the application of geographical knowledge and skills. To come up with solutions (...) to real-world social, economic and environmental problems. The study focused on the use of geographic information systems in analyzing the geographic calendar of rental offices in the city of Abha, relying on the most important applied aspects of geographic information systems represented in spatial analysis. To reveal the characteristics of the spatial distribution of rental offices and their distribution pattern, and to evaluate the efficiency of their distribution according to the local standard. The study came out with a number of results and recommendations, and also verified the hypotheses assumed by the researchers. (shrink)

Plant production is diverse in the Asir region, and there are many methods of analysis. Perhaps factor analysis is one of the most important statistical methods through which productive power can be measured in various geographical regions. In this study, factor analysis was used to measure the developments of plant production in the agricultural sector in the Asir region, Saudi Arabia. The factor analysis showed the presence of three main factors that together explained about %86.55 of the total variation in (...) the development of plant production in the governorates of the Asir region. The study showed three mathematical algorithms that can measure the development of plant production in the Asir region according to the three main factors: First factor equation λ1=44.250%=-0.521*X_1 0.810*X_2+0.78*X_3+0.842*X_4+0.755*X_5 Second factor equation λ2=24.960%-0.228*X_1+0.352*X_2+0.936*X_3-0.226*X_4-0.380*X_5 The third factor equation λ3=17.344%0.796*X_1+0.291*X_2+0.104*X_3+0.339*X_4-0.153*X_5 -The study classified the governorates of the Asir region, based on the results of the analysis, into three groups, according to negative and positive 0.933-0.975 and includes Bisha - Abha - Ahad Rafaida - Khamis Mushait - in Al-Furn - Al-Barak, while the second group represents the category of 0.897-0.548 and includes the governorates of Mahayel, Asir - Tanmomah - Al-Namas - Tathleeth. The third group includes the category of 0.255--0234 and includes the governorates Sarat Ubaidah - Al-Majadra and Bariq - Tareeb - Dhahran Al-Janoub and Al-Harajah - Rijal Almaa. (shrink)

In this paper, we present a dialectical argument for a priori skepticism (i.e. the thesis that we can be skeptical about a priori knowledge). Then, we propose a framework that combines elements from inferential contextualism and logical conventionalism to offer a weak transcendental argument against a priori skepticism.

Germain Grisez’s philosophical argument for respecting human life has been developed by fellow new natural law theorists and applied to a range of lethal actions, for its conclusion is vast: intending the death of any human being as a means or an end is wrong in itself. For some Thomists, the NNL view on killing is both lax and rigorist: They consider it lax because its narrow criterion for what is “intended” leaves out some acts, especially ones related to abortion, (...) that the critics consider murder. And they consider the NNL view rigorist insofar as it apparently rules out the death penalty, contrary to the Thomistic tradition and perhaps even heretically. However, the most salient philosophical arguments for exceptions to the principle against intending anyone’s death are weaker than the case for any given premise of the contrary NNL argument. Nevertheless, some NNL theorists’ arguments on life are unsound, some can be defended better than they have been, and some nonphilosophical objections based on theological authority require more exploration. (shrink)

Disintegration is the most important step for drug bioavailability because after, the disintegration process, the ingredients of solid dosage forms dissolve and become bioavailable. Generally, the tablets and capsules should be taken with a glass of water otherwise the manufacturer gives instructions to use the proper beverage. Several drugs are taken with different forms of beverages to ensure easy swallowing of the tablet, masking the bad taste of the drug and overcoming the drug aftertaste, these beverages can influence the disintegration (...) of the solid dosage form. The most common cold beverages consumed by the Libyan population are juice, milk, and Coca-Cola. These beverages are consumed without awareness of the possible effect of these beverages on drugs, especially over-the-counter drugs such as analgesic, antipyretic, and anti-inflammatory drugs that are taken without a prescription. This study aimed to evaluate the influence of three beverages, namely: orange juice, milk, and Coca-Cola on the disintegration time of four over-the-counter-drugs: Panadol, Congestal, Brufen, and Reality Extra using disintegration test of drugs in 0.1 N HCL and in hybrid medium prepared by combination of 150 ml 0.1 N HCL and 550 ml of beverage to simulate in vivo condition. The findings show that the orange juice significantly increases the disintegration time of all the investigated drugs. Coca-Cola significantly increases the disintegration time of Reality Extra, and slightly increases the disintegration time of Brufen, Congestal, and Panadol and the full-fat milk significantly increases the disintegration time of Reality Extra and Panadol while slightly increasing the disintegration time for Brufen and Congestal. It is concluded that commonly used beverages affect the disintegration time of the examined over-the-counter drugs. Patients should be advised to take these medications without beverages which may delay the disintegration and the onset of action of the drug. (shrink)

Diabetic ketoacidosis is a serious, medical emergency that can be fatal but treatable, we aimed to evaluate the clinical profile of patients admitted with diabetic ketoacidosis. This case series study enrolled 213 non-pregnant adult and adolescent patients admitted with diabetic ketoacidosis at Tripoli Diabetes Hospital from January to September 2023. Demographic data, clinical characteristics, laboratory findings, precipitating factors, and patient outcomes were extracted from medical records and analyzed. Type 1 diabetes mellitus was present in 187 (87.8%) of patients, the age (...) range 11-84 years, (30.26±13.28), with 130 patients ≤30 years old (61.0%), females accounting for 110 of the patients (51.6%), 109 had a diabetes duration of less than 10 years (51.2%). The most common precipitating factor was insulin omission 92 (43.2%) in patients with known diabetes mellitus, whereas, diabetic ketoacidosis as the first presentation of diabetes mellitus in 24 patients (11.7%), systolic blood pressure ranged 50-160 mmHg (112.82±16.19), diastolic blood pressure varied 30-100 mmHg (70.24±11.32). Plasma glucose at presentation ranged 183-1494 mg/dl (462.92±169.85), with Eu-glycemic diabetic ketoacidosis 100-249 mg/dl were in nine patients (4.2%), whereas most of cases (135 patients, 63.4%) present with plasma glucose 250-500 mg/dl, while hyperosmolar status (≥701 mg/dl) were present in 13 patients (6.1%). Venous pH varied from 6.7-7.42 (7.13±0.14), 132 (62.0%) patients presented with pH <7.24, while severe acidosis was pH < 7 in 32 of patients (14.6%), serum bicarbonate with 10.93±4.95, severe (<5 mmol) in 91 patients (42.7%) and moderate (5-10 mmol) were in 79 patients (37.08%). The mean length of hospital stay was 3.33 days, with an average of 2.11 days spent in the high-dependent unit. Serum potassium varied from 2.4-6.7 meq/L with 3.66± 0.63, most common complications of diabetic ketoacidosis treatment were hypokalemia observed in 82 (35.7%) of cases, and hypoglycemia was detected in 41 patients (19.2%). 170 patients were discharged in good condition (79.8%), and 17.8% of patients were transferred to another hospital to receive further management for co-morbid diseases with diabetes after controlling their hyperglycemic crises. The majority of patients presented with the critical status of diabetic ketoacidosis. The findings emphasize the importance of patient education about prevention measures prompt presentation to the hospital, and clinicians' awareness for early and aggressive treatment of hyperglycemic crises. (shrink)

Sporadic efforts have been made to introduce computational thinking methods into K-12 education in Palestine, but these have been held back by the challenging educational environment. However, a recent in-service training initiative, funded and organized by the Ministry or Education of Palestine, constitutes a significant effort to embed computational thinking in K-12 practice. The middle school teachers who participated in the training course were invited to participate in the present study, and 38 did so. A qualitative approach involving both interviews (...) with teachers and classroom observations was used in data collection. All the teachers agreed to be observed in their classrooms, while 20 of the 38 also agreed to participate in the interviews. The findings showed that teachers of a range of topics, including social sciences and languages, employed computational thinking skills in teaching their students, but they were confronted by a number of challenges, including technical infrastructure and support, and a lack of time to prepare CT classes and space in the curriculum to deliver them. The results indicate that the most appropriate action to support teachers’ delivery of CT would be to provide peer exchanges and expert coaching in the integration of CT in the curriculum. (shrink)

al-kitāb 1. Madkhal li-ʻilm al-qānūn (2. v.).

Transfer RNA (tRNA) modifications play an important role in regulating mRNA translation at the codon level. tRNA modifications can influence codon selection and optimality, thus shifting translation toward specific sets of mRNAs in a dynamic manner. Queuosine (Q) is a tRNA modification occurring at the wobble position. In eukaryotes, queuosine is synthesized by the tRNA‐guanine trans‐glycosylase (TGT) complex, which incorporates the nucleobase queuine (or Qbase) into guanine of the GUN anticodons. Queuine is sourced from gut bacteria and dietary intake. Q (...) was recently shown to be critical for cellular responses to oxidative and mitochondrial stresses, as well as its potential role in neurodegenerative diseases and brain health. These unique features of Q provide an interesting insight into the regulation of mRNA translation by gut bacteria, and the potential health implications. In this review, Q biology is examined in the light of recent literature and nearly 4 decades of research. Q's role in neuropsychiatric diseases and cancer is highlighted and discussed. Given the recent interest in Q, and the new findings, more research is needed to fully comprehend its biological function and disease relevance, especially in neurobiology. (shrink)

Purpose Advances in electronic performance monitoring have raised employees’ concerns regarding the invasion of privacy and erosion of trust. On the other hand, EPM promises to improve performance and processes. This paper aims to focus on how the alignment of EPM design and organizational culture through effective organizational mechanisms can address privacy concerns, and, hence, positively affect employees’ perception toward technology. Design/methodology/approach Based on a theoretical lens extending two conceptual frameworks, a qualitative approach was used to analyze interview data collected (...) from a comparative case study of two organizations in the USA and Qatar within the oil and gas sector. These two contexts were selected to emphasize the cross-cultural and organizational differences in employees’ acceptance of EPM. Findings The study revealed that national and corporate cultures affected employees’ perception and acceptance of monitoring in both countries. Because of diversity, though EPM was better accepted in Qatar, as they are an easy way to enforce standardization and to push employees to adapt to a dominating corporate culture. Conversely, in the USA where culture is more innovation-oriented, organizational mechanisms shifted the perceptions of EPM to being mean to obtain feedback rather than to impose standards. Research limitations/implications This qualitative study is based on a descriptive comparative case study of two organizations with two cultural contexts. The limited sample size and cross-sectional nature of data may need to be extended to a larger cultural scope that is observed over a longer period to safely generalize the findings. Practical implications Decision-makers in multinational corporations with different cultural backgrounds may benefit of this study’s outcomes, as it emphasizes the importance of the fit between EPM designs and the cultural settings. Furthermore, organizations aiming to conduct analytics on EPM data have to justify and prove its benefits to employees to facilitate acceptance. Social implications The study shows that employees in Qatar have a different cultural frame of reference in their perception of fairness and ethics than their counterparts in the USA because of changes in the meaning of social relations, personal goals and behavioral norms. Originality/value The originality of this study lays in its empirical validation of a composite framework examining both national and corporate cultures on employees’ reactions to EPM systems. It also proves the critical importance of organizational mechanisms to align the EPM design with the organization cultural settings. (shrink)

Abdel-Hakim Ourghi's Reform of Islam is an open indictment of prevailing conservative Islam which insists on the absolute subjugation of the body and mind of all Muslims. The author seeks a humanist understanding of Islam and aims to interpret Islam in today's terms. He argues against the historical alienation and transfiguration that still shape the collective consciousness of Muslims in the 21st Century. Using critical analysis and logic, the author aims to reveal the true core of Islam. His 40 (...) Theses include: The freedom of the individual to interpret the Qur'an No scholars as mediators between God and man Islam does not claim to possess the absolute truth Only a reformed and open Islam is a religion of peace The Qur'an as the basis of a contemporary humanist ethics. (shrink)

This article offers an account of the responsibility that individuals bear by virtue of their national belonging alone. Via their national pride, the living connect themselves actively with select actions performed by others who might long be dead. They imagine themselves as having won past wars, built ancient empires and the like. This same feat of their imagination imposes on them a responsibility for the bad outcomes that were brought about through their imagined exploits. Their national responsibility for the "sins (...) of the fathers" however lends itself only to the kinds of responses that these living agents can demand of themselves. While their national responsibility can be captured by either the vocabulary of guilt or that of shame, the latter turns out to be more promising as it better accounts for the strong hold that the national idea has on contemporary political thinking. (shrink)

This book explores emerging conflicts about religious liberty and discrimination. In point-counterpoint format, it brings together longtime LGBT rights advocate John Corvino and rising conservative thinkers Ryan T. Anderson and Sherif Girgis to debate Religious Freedom Restoration Acts, anti-discrimination law, and age-old questions about identity, morality, and society.

This dissertation engages the following question: how, in the absence of an uncontroversial source of moral guidance, can liberals make political and moral claims across cultural divides? While committed to toleration, liberals cannot escape the compulsion to apply basic standards of equal individual human rights and liberties universally. Under postmetaphysical conditions, however, they no longer find credible arguments that assure them of the sources of these standards in "natural law," "human nature," or "practical reason." Aware that individual rights have their (...) provenance in modern "Western" history, liberals fear being intolerant when they apply these standards universally, and experience as a result a problem of cross-cultural judgement. ;In this project I engage in a sympathetic critique of Richard Rorty's, Jurgen Habermas's and John Rawls's attempts at addressing this problem and provide a fourth alternative that cannot be absorbed by any of their frameworks. Rorty offers liberals the comforts of ethnocentrism. He assures them that political and moral judgements are always made by someone from somewhere. For this comfort, however, he extracts the exorbitant ethical price of other-disregard. Habermas derives individual rights from the universal practice of argumentation. By relying on the overly exacting standard of "rational consensus," however, he limits the applicability of his answer to liberal secular contexts. In his free-standing answer, Rawls offers the promising standard of an "overlapping consensus." His overly static use of this concept, however, drains it of its promise. ;Drawing on each of these attempts as well as on Aristotle's Rhetoric, I offer the alternative of a political project of moral persuasion. Instead of seeking to address the problem of cross-cultural judgement by coup de plume, liberals' best hope is to obviate it in practice, by forging a global, minimally liberal, overlapping consensus. As moral persuaders liberals would intrude actively in nonliberal debates and would seek to convince nonliberals from within their various lights, of the worthiness of the commitment to the freedom and equality of persons. (shrink)

In her book, Geraldine Brooks fails to distinguish between what Islam says and what Muslims do.

The teachings, style and impact of the Qur'an have always been matters of controversy, among both Muslims and non-Muslims. But in a modern context of intercultural sensitivity, what the Qur'an says and means are perhaps more urgent questions than ever before. This major new book by one of the world's finest Islamic scholars responds to that urgency. Building on his earlier groundbreaking work, the author challenges misinterpretations of particular Qur'anic verses from whatever quarter. He addresses the infamous 'sword' verse, frequently (...) cited as a justification for jihad. He also questions the 'tribute' verse, associated with the Muslim state subjugating Jews and Christians; and the idea of Paradise in the Qur'an, often viewed by the West as emphasising merely physical pleasures, or used by Islamic fighters as their just reward for holy war. The author argues that wrenching the verses out of the context of the whole has led to dangerous ideologies being built on isolated phrases which have then assumed afterlives of their own. This nuanced, holistic reading has vital interfaith ramifications. (shrink)

Malaysia, in the Malaysia Urban Forum 2019 aims torealize the vision of the World Urban Forum 2018 theme of ‘Cities2030, Cities for All: Implementing the New Urban Agenda’ that is in line withSustainable Development Goals. The introduction of the MalaysianStandard started in 1990 but not acknowledged until the establishment of thePersons with Disabilities Act in 2008 and gazetted in the Uniform Building By-Laws amendments despite the slow pace of accessibility awarenessin urban development and implementation. The methodology compares theestablishment of notable (...) Inclusive and Accessible Cities with their planningstrategies of implementing Universal Design. Findings and results willdetermine inclusive city’s strategies from each case study documented anddevice a framework of projection for cities’ inclusivity. Conclusively, this studywould determine the anticipation of Malaysian urban cities to be Inclusive andAccessible in 2030 by strategising action plans and a framework for ten year planning. (shrink)

This article explains how we ordinary subjects of a state who are neither political leaders nor functionaries are responsible for outcomes that are properly attributed to that state and that took place during our adult lifetime. Its focus is on the connection we forge to those outcomes via our obedience alone. If our responsibility as subjects is justified, it would apply under all regime types including oppressive and authoritarian ones. The argument is that this responsibility can only be justified within (...) a minimal account of agency and a bare-bones account of responsibility. Thus, while we incur a burden of responsibility for the state via our obedience alone, that burden does not suffice to either blame us or extract remedies from us for state injustices. For us obedient subjects, however, it is important that we be cognizant of this burden as it marks the most minimal agency we exercise in the state. (shrink)

We show in this paper how three continental philosophers (Husserl, Heidegger, and Derrida respectively) respond negatively to the analytic correspondence theory of truth using different notions developed by them (i.e. the notion of Intentionality by Husserl, the notion of Dasein by Heidegger, and the notion of Trace by Derrida). We show that despite the fact that the three philosophers are united against the analytic correspondence theory of truth, there are still deep differences between them which stem from the different tools (...) they use to articulate the concept of truth. Also, we argue that Husserlian truth has an advantageous position over the other concepts of truth presented. (shrink)

The Hipparchus features a conversation between Socrates and an un-named companion, at an unknown time and place, about gain and whether we should in any way limit our pursuit of gain. Socrates argues intransigently that we should not place any limits on our pursuit of gain, while the companion, despite being unable to counter his arguments, is equally firm in his rejection of Socrates’ moral position. The dialogue thus shows the strength of the conviction, in the souls of decent people, (...) that unrestrained pursuit of the good things is not good for you. This conviction exists prior to calculation, and the action of the dialogue thereby testifies to the existence of man’s natural conscience. (shrink)

The translation of Apology 30b 2–4 has long been controversial. The standard translation of this sentence reveals a Socrates who wants to highlight a problem about virtue by making an extremely optimistic statement about it; the alternative translation supported by Myles Burnyeat and Christopher Rowe would suppress the problem by appearing to resolve it. A detailed examination of Socrates’ speech at 28b–31c, defending the nobility of his Delphic activity, finds fault with the resolution proposed by Burnyeat and Rowe, shows how (...) Socrates’ speech is informed by his clear awareness of human hopes for virtue, highlights his clarity about his situation, and addresses the question of the character of the Socratic virtue or toughness that is the by-product of his activity. (shrink)

The political unaccountability of ordinary citizens in classical Athens was originally raised as a challenge by ancient critics of democracy. In tension with that criticism, the authors argue that attention to the above challenge is consistent with a defence of Athenian democratic politics. In fact, ordinary citizens' function in the Assembly and courts implicitly included the burden of justifying their own political decisions to an imagined authority, as if they could be brought to account. Byeans of practices that encouraged this (...) self-scrutiny, Athenians marked the challenge of citizens' political unaccountability as an unavoidable but manageable aspect of their democracy. (shrink)

BackgroundBoth reducing sitting and increasing physical exercise promote health but exercising more does not necessarily reduce sitting time. One reason for this non-dependency may be that different aspects of exercise motivation are differently related to sitting time. Identifying the type of exercise motivation that would also be associated with sitting time can help to reduce sitting indirectly through increased exercise, thus bringing greater benefits.MethodsThe present study explored the association between quality of motivations toward physical activity with physical activity and sitting (...) time in a total of 373 adults. The short version of international physical activity questionnaire was used for measuring physical activity and sitting time. Reasons for exercising regularly were measured with the Self-Regulated Questionnaire–Exercise, including four regulation subscales to assess regulation styles. Confirmatory factor analysis was used to test the four subscales of SRQ-E with the data obtained using AMOS v.23. Then, structural equation model with maximum likelihood estimates was used to test the hypothesized model.ResultsThe results indicated that only intrinsic motivation, but not identified, introjected or external motivation, toward physical activity predicted both physical activity and sitting time. Higher intrinsic motivation toward physical activity was associated with both higher physical activity and lower sitting time. In addition, physical activity was a mediator for lower sitting time when the source was intrinsic motivation.ConclusionPrevious studies have shown low between and within participant correlation between sitting time and physical activity, and interventions have generally failed to both increase physical activity while decreasing sitting time. The present cross-sectional results suggest that targeting increased physical activity by increased intrinsic motivation has the potential to both increase physical activity and decrease sitting time. (shrink)

Big Data is a large-sized and complex dataset, which cannot be managed using traditional data processing tools. Mining process of big data is the ability to extract valuable information from these large datasets. Association rule mining is a type of data mining process, which is indented to determine interesting associations between items and to establish a set of association rules whose support is greater than a specific threshold. The classical association rules can only be extracted from binary data where an (...) item exists in a transaction, but it fails to deal effectively with quantitative attributes, through decreasing the quality of generated association rules due to sharp boundary problems. In order to overcome the drawbacks of classical association rule mining, we propose in this research a new neutrosophic association rule algorithm. The algorithm uses a new approach for generating association rules by dealing with membership, indeterminacy, and non-membership functions of items, conducting to an efficient decision-making system by considering all vague association rules. To prove the validity of the method, we compare the fuzzy mining and the neutrosophic mining. The results show that the proposed approach increases the number of generated association rules. (shrink)

Uchiyama et al. describe how a more complete measurement of the dynamic nature of culture could help us unmask the true richness of genetic effects on behaviour. I underscore this notion here by reflecting on the role that the dynamic relationship between culture and DNA has played in our evolutionary history and will play in our evolutionary future.